Flagellar cAMP signaling controls trypanosome progression through host tissues

Trypanosoma brucei probably relies on chemotactic signals for movement through tsetse fly tissues, but the molecular basis is unknown. Here, the authors show that flagellar cAMP signaling is required for traversal of the peritrophic matrix and that, without it, parasites are trapped in the midgut lu...

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Bibliographic Details
Main Authors: Sebastian Shaw, Stephanie F. DeMarco, Ruth Rehmann, Tanja Wenzler, Francesca Florini, Isabel Roditi, Kent L. Hill
Format: Article
Language:English
Published: Nature Publishing Group 2019-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08696-y

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