Chronic recurrent multifocal osteomyelitis, central retinal artery occlusion and optic neuropathy: A new association

Chronic recurrent multifocal osteomyelitis, central retinal artery occlusion and optic neuropathy: A new association

Purpose: To report a patient with chronic recurrent multifocal osteomyelitis (CRMO) complicated by optic neuropathy and central retinal artery occlusion (CRAO). Observations: CRMO is a noninfectious, inflammatory bone disorder. It is thought to be an autoimmune condition related to an imbalance of p...

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Main Authors: Michael S. Vaphiades, Kevin E. Lai, Lanning B. Kline, Brendan Grondines, Emily Riser
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
Chronic recurrent multifocal osteomyelitis
Central retinal artery occlusion
Optic neuropathy
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993621002188
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spelling doaj-30f104223c4d4f55b7696661ee9859552021-09-23T04:40:07ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362021-12-0124101209Chronic recurrent multifocal osteomyelitis, central retinal artery occlusion and optic neuropathy: A new associationMichael S. Vaphiades0Kevin E. Lai1Lanning B. Kline2Brendan Grondines3Emily Riser4Departments of Ophthalmology, University of Alabama, Birmingham, AL, USA; Departments of Neurology, University of Alabama, Birmingham, AL, USA; Corresponding author D.O. UAB Department of Ophthalmology Suite 601 700 South 18th Street Birmingham, AL, 35233, USA.Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, IN, USA; Ophthalmology Service, Richard L. Roudebush Veterans Administration Medical Center, Indianapolis, IN, USA; Neuro-Ophthalmology Section, Midwest Eye Institute, Carmel, IN, USADepartments of Ophthalmology, University of Alabama, Birmingham, AL, USADepartments of Ophthalmology, University of Alabama, Birmingham, AL, USADepartments of Neurology, University of Alabama, Birmingham, AL, USAPurpose: To report a patient with chronic recurrent multifocal osteomyelitis (CRMO) complicated by optic neuropathy and central retinal artery occlusion (CRAO). Observations: CRMO is a noninfectious, inflammatory bone disorder. It is thought to be an autoimmune condition related to an imbalance of pro- and anti-inflammatory cytokines. Retinal vasculitis has been reported in a patient with CRMO but not CRAO or optic neuropathy. Conclusions: We expanded the list of ophthalmic involvement of CRMO to include CRAO and optic neuropathy.http://www.sciencedirect.com/science/article/pii/S2451993621002188Chronic recurrent multifocal osteomyelitisCentral retinal artery occlusionOptic neuropathy
collection DOAJ
language English
format Article
sources DOAJ
author Michael S. Vaphiades
Kevin E. Lai
Lanning B. Kline
Brendan Grondines
Emily Riser
spellingShingle Michael S. Vaphiades
Kevin E. Lai
Lanning B. Kline
Brendan Grondines
Emily Riser
Chronic recurrent multifocal osteomyelitis, central retinal artery occlusion and optic neuropathy: A new association
American Journal of Ophthalmology Case Reports
Chronic recurrent multifocal osteomyelitis
Central retinal artery occlusion
Optic neuropathy
author_facet Michael S. Vaphiades
Kevin E. Lai
Lanning B. Kline
Brendan Grondines
Emily Riser
author_sort Michael S. Vaphiades
title Chronic recurrent multifocal osteomyelitis, central retinal artery occlusion and optic neuropathy: A new association
title_short Chronic recurrent multifocal osteomyelitis, central retinal artery occlusion and optic neuropathy: A new association
title_full Chronic recurrent multifocal osteomyelitis, central retinal artery occlusion and optic neuropathy: A new association
title_fullStr Chronic recurrent multifocal osteomyelitis, central retinal artery occlusion and optic neuropathy: A new association
title_full_unstemmed Chronic recurrent multifocal osteomyelitis, central retinal artery occlusion and optic neuropathy: A new association
title_sort chronic recurrent multifocal osteomyelitis, central retinal artery occlusion and optic neuropathy: a new association
publisher Elsevier
series American Journal of Ophthalmology Case Reports
issn 2451-9936
publishDate 2021-12-01
description Purpose: To report a patient with chronic recurrent multifocal osteomyelitis (CRMO) complicated by optic neuropathy and central retinal artery occlusion (CRAO). Observations: CRMO is a noninfectious, inflammatory bone disorder. It is thought to be an autoimmune condition related to an imbalance of pro- and anti-inflammatory cytokines. Retinal vasculitis has been reported in a patient with CRMO but not CRAO or optic neuropathy. Conclusions: We expanded the list of ophthalmic involvement of CRMO to include CRAO and optic neuropathy.
topic Chronic recurrent multifocal osteomyelitis
Central retinal artery occlusion
Optic neuropathy
url http://www.sciencedirect.com/science/article/pii/S2451993621002188
work_keys_str_mv AT michaelsvaphiades chronicrecurrentmultifocalosteomyelitiscentralretinalarteryocclusionandopticneuropathyanewassociation
AT kevinelai chronicrecurrentmultifocalosteomyelitiscentralretinalarteryocclusionandopticneuropathyanewassociation
AT lanningbkline chronicrecurrentmultifocalosteomyelitiscentralretinalarteryocclusionandopticneuropathyanewassociation
AT brendangrondines chronicrecurrentmultifocalosteomyelitiscentralretinalarteryocclusionandopticneuropathyanewassociation
AT emilyriser chronicrecurrentmultifocalosteomyelitiscentralretinalarteryocclusionandopticneuropathyanewassociation
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