Nucleotide excision repair is a predictor of early relapse in pediatric acute lymphoblastic leukemia

Nucleotide excision repair is a predictor of early relapse in pediatric acute lymphoblastic leukemia

Abstract Background Nucleotide Excision Repair (NER) is a major pathway of mammalian DNA repair that is associated with drug resistance and has not been well characterized in acute lymphoblastic leukemia (ALL). The objective of this study was to explore the role of NER in relapsed ALL patients. We h...

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Bibliographic Details
Main Authors: Omar M. Ibrahim, Homood M. As Sobeai, Stephen G. Grant, Jean J. Latimer
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Medical Genomics
Subjects:
Nucleotide excision repair gene
Acute lymphoblastic leukemia
Childhood ALL
Precursor-B-ALL
Early relapse
Late relapse
Online Access:http://link.springer.com/article/10.1186/s12920-018-0422-2

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