Overexpression of Mucin 1 Suppresses the Therapeutical Efficacy of Disulfiram against Canine Mammary Tumor

Overexpression of Mucin 1 Suppresses the Therapeutical Efficacy of Disulfiram against Canine Mammary Tumor

Mucin 1 (MUC1), a transmembrane protein, is closely associated with the malignancy and metastasis of canine mammary tumors; however, the role of overexpressed MUC1 in the development of cancer cells and response to drug treatment remains unclear. To address this question, we developed a new canine m...

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Bibliographic Details
Main Authors: Ying Zhao, Zixiang Lin, Zhaoyan Lin, Chaoyu Zhou, Gang Liu, Jiahao Lin, Di Zhang, Degui Lin
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Animals
Subjects:
canine mammary tumor
Mucin 1
disulfiram
PI3K/Akt
apoptosis
Online Access:https://www.mdpi.com/2076-2615/11/1/37

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