Brain Activity of Thioctic Acid Enantiomers: In Vitro and in Vivo Studies in an Animal Model of Cerebrovascular Injury

Brain Activity of Thioctic Acid Enantiomers: In Vitro and in Vivo Studies in an Animal Model of Cerebrovascular Injury

Oxidative stress is an imbalance between the production of free radicals and antioxidant defense mechanisms, potentially leading to tissue damage. Oxidative stress has a key role in the development of cerebrovascular and/or neurodegenerative diseases. This phenomenon is mainly mediated by an enhance...

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Bibliographic Details
Main Authors: Seyed Khosrow Tayebati, Carlotta Marini, Innocent E. Nwankwo, Lorenzo Di Cesare Mannelli, Francesco Amenta, Valerio Farfariello, Consuelo Amantini, Daniele Tomassoni
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:International Journal of Molecular Sciences
Subjects:
oxidative stress
thioctic acid
brain
spontaneously hypertensive rats
PC12 cells
Online Access:http://www.mdpi.com/1422-0067/14/3/4580

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