Detailed evaluation of the upper airway in the Dp(16)1Yey mouse model of Down syndrome
Abstract A high prevalence of obstructive sleep apnea (OSA) has been reported in Down syndrome (DS) owing to the coexistence of multiple predisposing factors related to its genetic abnormality, posing a challenge for the management of OSA. We hypothesized that DS mice recapitulate craniofacial abnor...
Main Authors: | Tatsunori Takahashi, Noriaki Sakai, Tomonori Iwasaki, Timothy C. Doyle, William C. Mobley, Seiji Nishino |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2020-12-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-78278-2 |
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