Literature based drug interaction prediction with clinical assessment using electronic medical records: novel myopathy associated drug interactions.

Drug-drug interactions (DDIs) are a common cause of adverse drug events. In this paper, we combined a literature discovery approach with analysis of a large electronic medical record database method to predict and evaluate novel DDIs. We predicted an initial set of 13197 potential DDIs based on subs...

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Bibliographic Details
Main Authors: Jon D Duke, Xu Han, Zhiping Wang, Abhinita Subhadarshini, Shreyas D Karnik, Xiaochun Li, Stephen D Hall, Yan Jin, J Thomas Callaghan, Marcus J Overhage, David A Flockhart, R Matthew Strother, Sara K Quinney, Lang Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22912565/pdf/?tool=EBI