Non-natural and photo-reactive amino acids as biochemical probes of immune function.

Non-natural and photo-reactive amino acids as biochemical probes of immune function.

Wilms tumor protein (WT1) is a transcription factor selectively overexpressed in leukemias and cancers; clinical trials are underway that use altered WT1 peptide sequences as vaccines. Here we report a strategy to study peptide-MHC interactions by incorporating non-natural and photo-reactive amino a...

Full description

Bibliographic Details
Main Authors: Marta Gómez-Nuñez, Kurtis J Haro, Tao Dao, Deming Chau, Annie Won, Sindy Escobar-Alvarez, Victoriya Zakhaleva, Tatyana Korontsvit, David Y Gin, David A Scheinberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2592539?pdf=render

Internet

http://europepmc.org/articles/PMC2592539?pdf=render

Similar Items