An attempt to control schistosomiasis mansoni in an endemic area by the use of Hycanthone as chemotherapeutic agent

Hycanthone in a single dose of 3.3 mg/kg of body weight was used to treal mansoni schistosomiasis in 597 persons (83%) of the population of the endemic vilage of Canabrava. Ninety two patients received a 2nd course 14 months later. There was one death em the 2nd treatment. The cure rate after one st...

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Main Authors: J. C. Bina, Aluizio Preta
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 1974-08-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821974000400005
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spelling doaj-30cfa8245d3e43e29162c671b20acfaa2020-11-24T22:34:16ZengSociedade Brasileira de Medicina Tropical (SBMT)Revista da Sociedade Brasileira de Medicina Tropical0037-86821678-98491974-08-0184217222An attempt to control schistosomiasis mansoni in an endemic area by the use of Hycanthone as chemotherapeutic agentJ. C. BinaAluizio PretaHycanthone in a single dose of 3.3 mg/kg of body weight was used to treal mansoni schistosomiasis in 597 persons (83%) of the population of the endemic vilage of Canabrava. Ninety two patients received a 2nd course 14 months later. There was one death em the 2nd treatment. The cure rate after one stool examination was smaller after the 2ni treatment in comparison with the first one. Re-infections did not occur imediately after the treatment. Three years later the prevalence of persons passing eggs through one stool examination was 19% compared to the 46.3% before the treatment. Adults are more resistant to the re-infections than younger.<br>Hycanthone na dose de 3,3 mg/kg de peso corporal foi usado no tratamento de 597 (83%) pessoas da população da vila de Canabrava, onde a esqwistossomose é endêmica. Noventa e dois pacientes foram retratados após 14 meses. Houve um óbito após o retratamento. 0 19 exame de fezes revelou 0,7% de resultados positivos após o tratamento e 23% após o retratamento. As reinfecções não ocorrem imediatamente após o tratamento. Três anos após o tratamento inicial a prevalência de um exame de fezes positivo na poimlação era de 19% em comparação com 46% antes do tratamento. Os adultos são mais resistentes à reinfecção.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821974000400005
collection DOAJ
language English
format Article
sources DOAJ
author J. C. Bina
Aluizio Preta
spellingShingle J. C. Bina
Aluizio Preta
An attempt to control schistosomiasis mansoni in an endemic area by the use of Hycanthone as chemotherapeutic agent
Revista da Sociedade Brasileira de Medicina Tropical
author_facet J. C. Bina
Aluizio Preta
author_sort J. C. Bina
title An attempt to control schistosomiasis mansoni in an endemic area by the use of Hycanthone as chemotherapeutic agent
title_short An attempt to control schistosomiasis mansoni in an endemic area by the use of Hycanthone as chemotherapeutic agent
title_full An attempt to control schistosomiasis mansoni in an endemic area by the use of Hycanthone as chemotherapeutic agent
title_fullStr An attempt to control schistosomiasis mansoni in an endemic area by the use of Hycanthone as chemotherapeutic agent
title_full_unstemmed An attempt to control schistosomiasis mansoni in an endemic area by the use of Hycanthone as chemotherapeutic agent
title_sort attempt to control schistosomiasis mansoni in an endemic area by the use of hycanthone as chemotherapeutic agent
publisher Sociedade Brasileira de Medicina Tropical (SBMT)
series Revista da Sociedade Brasileira de Medicina Tropical
issn 0037-8682
1678-9849
publishDate 1974-08-01
description Hycanthone in a single dose of 3.3 mg/kg of body weight was used to treal mansoni schistosomiasis in 597 persons (83%) of the population of the endemic vilage of Canabrava. Ninety two patients received a 2nd course 14 months later. There was one death em the 2nd treatment. The cure rate after one stool examination was smaller after the 2ni treatment in comparison with the first one. Re-infections did not occur imediately after the treatment. Three years later the prevalence of persons passing eggs through one stool examination was 19% compared to the 46.3% before the treatment. Adults are more resistant to the re-infections than younger.<br>Hycanthone na dose de 3,3 mg/kg de peso corporal foi usado no tratamento de 597 (83%) pessoas da população da vila de Canabrava, onde a esqwistossomose é endêmica. Noventa e dois pacientes foram retratados após 14 meses. Houve um óbito após o retratamento. 0 19 exame de fezes revelou 0,7% de resultados positivos após o tratamento e 23% após o retratamento. As reinfecções não ocorrem imediatamente após o tratamento. Três anos após o tratamento inicial a prevalência de um exame de fezes positivo na poimlação era de 19% em comparação com 46% antes do tratamento. Os adultos são mais resistentes à reinfecção.
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86821974000400005
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