LncRNA PVT1 Knockdown Ameliorates Myocardial Ischemia Reperfusion Damage via Suppressing Gasdermin D-Mediated Pyroptosis in Cardiomyocytes

LncRNA PVT1 Knockdown Ameliorates Myocardial Ischemia Reperfusion Damage via Suppressing Gasdermin D-Mediated Pyroptosis in Cardiomyocytes

Objective: Myocardial ischemia reperfusion (I/R) damage is a life-threatening vascular emergency after myocardial infarction. Here, we observed the cardioprotective effect of long non-coding RNA (lncRNA) PVT1 knockdown against myocardial I/R damage.Methods: This study constructed a myocardial I/R-in...

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Bibliographic Details
Main Authors: Cuizhi Li, Huafeng Song, Chunlin Chen, Shaoxian Chen, Qiyu Zhang, Dehui Liu, Jinglong Li, Haojian Dong, Yueheng Wu, Youbin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
lncRNA
PVT1
myocardial ischemia reperfusion
pyroptosis
gasdermin D
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.747802/full

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