The mitochondrial complex I activity is reduced in cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function.

The mitochondrial complex I activity is reduced in cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function.

Cystic fibrosis (CF) is a frequent and lethal autosomal recessive disease. It results from different possible mutations in the CFTR gene, which encodes the CFTR chloride channel. We have previously studied the differential expression of genes in CF and CF corrected cell lines, and found a reduced ex...

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Bibliographic Details
Main Authors: Angel G Valdivieso, Mariángeles Clauzure, María C Marín, Guillermo L Taminelli, María M Massip Copiz, Francisco Sánchez, Gustavo Schulman, María L Teiber, Tomás A Santa-Coloma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3504030?pdf=render

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http://europepmc.org/articles/PMC3504030?pdf=render

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