Evaluation of the Inhibitory Effects of (E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(naphthalen-1-yl)prop-2-en-1-one (DiNap), a Natural Product Analog, on the Replication of Type 2 PRRSV In Vitro and In Vivo

Evaluation of the Inhibitory Effects of (E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(naphthalen-1-yl)prop-2-en-1-one (DiNap), a Natural Product Analog, on the Replication of Type 2 PRRSV In Vitro and In Vivo

DiNap [(E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(naphthalen-1-yl)prop-2-en-1-one], an analog of a natural product (the chalcone flavokawain), was synthesized and characterized in this study. Porcine reproductive and respiratory syndrome virus (PRRSV) is the most challenging threat to the swine indust...

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Bibliographic Details
Main Authors: Amina Khatun, Sun You Park, Nadeem Shabir, Salik Nazki, A-Rum Kang, Chang-Gi Jeong, Byoung-Joo Seo, Myeon-Sik Yang, Bumseok Kim, Young Ho Seo, Won-Il Kim
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Molecules
Subjects:
antiviral therapeutics
DiNap
PRRSV
VR2332
pigs
Online Access:http://www.mdpi.com/1420-3049/24/5/887

Internet

http://www.mdpi.com/1420-3049/24/5/887

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