Broad CTL Response in Early HIV Infection Drives Multiple Concurrent CTL Escapes.

Recent studies have highlighted the ability of HIV to escape from cytotoxic T lymphocyte (CTL) responses that concurrently target multiple viral epitopes. Yet, the viral dynamics involved in such escape are incompletely understood. Previous analyses have made several strong assumptions regarding HIV...

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Bibliographic Details
Main Authors: Sivan Leviyang, Vitaly V Ganusov
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4624722?pdf=render