Chronic osteo-articular changes in patients with sickle cell disease

Abstract Background Sickle cell disease (SCD) is an autosomal recessive genetic disease in which a mutation occurs in the β-globin chain gene, resulting in abnormal hemoglobin levels. In an environment with reduced oxygen concentration, red blood cells change their conformation, resulting in chronic...

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Bibliographic Details
Main Authors: Taciana Fernandes Araújo Ferreira, Ana Paula Teixeira dos Santos, Alexandra Silva Leal, Gilberto de Araújo Pereira, Sheila Soares Silva, Helio Moraes-Souza
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Advances in Rheumatology
Subjects:
Online Access:https://doi.org/10.1186/s42358-021-00169-5