Class I HLA Allele Predicted Restricted Antigenic Coverages for Spike and Nucleocapsid Proteins Are Associated With Deaths Related to COVID-19

Class I HLA Allele Predicted Restricted Antigenic Coverages for Spike and Nucleocapsid Proteins Are Associated With Deaths Related to COVID-19

The world is dealing with one of the worst pandemics ever. SARS-CoV-2 is the etiological agent of COVID-19 that has already spread to more than 200 countries. However, infectivity, severity, and mortality rates do not affect all countries equally. Here we consider 140 HLA alleles and extensively inv...

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Bibliographic Details
Main Authors: Marco Antônio M. Pretti, Rômulo G. Galvani, Gustavo Fioravanti Vieira, Adriana Bonomo, Martín H. Bonamino, Mariana Boroni
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
COVID-19
SARS-CoV-2
Betacoronavirus
ligandome
population coverage analysis
herd immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.565730/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.565730/full

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