Irreversible electroporation ablation overcomes tumor-associated immunosuppression to improve the efficacy of DC vaccination in a mice model of pancreatic cancer

Irreversible electroporation ablation overcomes tumor-associated immunosuppression to improve the efficacy of DC vaccination in a mice model of pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is associated with highly immunosuppressive tumor microenvironment (TME) that can limit the efficacy of dendritic cell (DC) vaccine immunotherapy. Irreversible electroporation (IRE) is a local ablation approach. Herein, we test the hypothesis that IRE ablation...

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Bibliographic Details
Main Authors: Jia Yang, Aydin Eresen, Junjie Shangguan, Quanhong Ma, Vahid Yaghmai, Zhuoli Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:OncoImmunology
Subjects:
irreversible electroporation
dendritic cell vaccine
pancreatic ductal adenocarcinoma
magnetic resonance imaging
Online Access:http://dx.doi.org/10.1080/2162402X.2021.1875638

Internet

http://dx.doi.org/10.1080/2162402X.2021.1875638

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