Polycystic kidney disease in the medaka (Oryzias latipes) pc mutant caused by a mutation in the Gli-Similar3 (glis3) gene.

Polycystic kidney disease (PKD) is a common hereditary disease in humans. Recent studies have shown an increasing number of ciliary genes that are involved in the pathogenesis of PKD. In this study, the Gli-similar3 (glis3) gene was identified as the causal gene of the medaka pc mutant, a model of P...

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Main Authors: Hisashi Hashimoto, Rieko Miyamoto, Naoki Watanabe, Dai Shiba, Kenjiro Ozato, Chikako Inoue, Yuko Kubo, Akihiko Koga, Tomoko Jindo, Takanori Narita, Kiyoshi Naruse, Kazuko Ohishi, Keiko Nogata, Tadasu Shin-I, Shuichi Asakawa, Nobuyoshi Shimizu, Tomotsune Miyamoto, Toshio Mochizuki, Takahiko Yokoyama, Hiroshi Hori, Hiroyuki Takeda, Yuji Kohara, Yuko Wakamatsu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2706989?pdf=render