Overexpression of endothelial β3‐adrenergic receptor induces diastolic dysfunction in rats

Overexpression of endothelial β3‐adrenergic receptor induces diastolic dysfunction in rats

Abstract Aims Diastolic dysfunction is common in cardiovascular diseases, particularly in the case of heart failure with preserved ejection fraction. The challenge is to develop adequate animal models to envision human therapies in the future. It has been hypothesized that this diastolic dysfunction...

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Bibliographic Details
Main Authors: Justine Dhot, Marine Ferron, Valentine Prat, Antoine Persello, David Roul, David Stévant, Damien Guijarro, Nicolas Piriou, Virginie Aillerie, Angélique Erraud, Gilles Toumaniantz, Morteza Erfanian, Angela Tesse, Amandine Grabherr, Laurent Tesson, Séverine Menoret, Ignacio Anegon, Jean‐Noël Trochu, Marja Steenman, Michel De Waard, Bertrand Rozec, Benjamin Lauzier, Chantal Gauthier
Format: Article
Language:English
Published: Wiley 2020-12-01
Series:ESC Heart Failure
Subjects:
Diastolic dysfunction
Endothelium
Nitric oxide production
HFpEF
Transcriptome
β3‐Adrenoceptor
Online Access:https://doi.org/10.1002/ehf2.13040

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