PALTEM: What Parameters Should Be Collected in Disaster Settings to Assess the Long-Term Outcomes of Famine?

PALTEM: What Parameters Should Be Collected in Disaster Settings to Assess the Long-Term Outcomes of Famine?

Evidence suggests that nutritional status during fetal development and early life leaves an imprint on the genome, which leads to health outcomes not only on a person as an adult but also on his offspring. The purpose of this study is to bring forth an overview of the relevant parameters that need t...

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Bibliographic Details
Main Authors: Alexandra Moraru, Maria Moitinho de Almeida, Jean-Marie Degryse
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:International Journal of Environmental Research and Public Health
Subjects:
environmental epigenetics
DNA methylation
life-stage exposure
famine
risk assessment
Online Access:http://www.mdpi.com/1660-4601/15/5/857
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spelling doaj-30347a92c45a431daa677b09a53ade742020-11-25T01:11:32ZengMDPI AGInternational Journal of Environmental Research and Public Health1660-46012018-04-0115585710.3390/ijerph15050857ijerph15050857PALTEM: What Parameters Should Be Collected in Disaster Settings to Assess the Long-Term Outcomes of Famine?Alexandra Moraru0Maria Moitinho de Almeida1Jean-Marie Degryse2Centre for Research on the Epidemiology of Disasters, Université Catholique de Louvain, Brussels 1200, BelgiumCentre for Research on the Epidemiology of Disasters, Université Catholique de Louvain, Brussels 1200, BelgiumInstitute of Health and Society, Université Catholique de Louvain, Brussels 1200, BelgiumEvidence suggests that nutritional status during fetal development and early life leaves an imprint on the genome, which leads to health outcomes not only on a person as an adult but also on his offspring. The purpose of this study is to bring forth an overview of the relevant parameters that need to be collected to assess the long-term and transgenerational health outcomes of famine. A literature search was conducted for the most pertinent articles on the epigenetic effects of famine. The results were compiled, synthesized and discussed with an expert in genetics for critical input and validation. Prenatal and early life exposure to famine was associated with metabolic, cardiovascular, respiratory, reproductive, neuropsychiatric and oncologic diseases. We propose a set of parameters to be collected in disaster settings to assess the long-term outcomes of famine: PALTEM (parameters to assess long-term effects of malnutrition).http://www.mdpi.com/1660-4601/15/5/857environmental epigeneticsDNA methylationlife-stage exposurefaminerisk assessment
collection DOAJ
language English
format Article
sources DOAJ
author Alexandra Moraru
Maria Moitinho de Almeida
Jean-Marie Degryse
spellingShingle Alexandra Moraru
Maria Moitinho de Almeida
Jean-Marie Degryse
PALTEM: What Parameters Should Be Collected in Disaster Settings to Assess the Long-Term Outcomes of Famine?
International Journal of Environmental Research and Public Health
environmental epigenetics
DNA methylation
life-stage exposure
famine
risk assessment
author_facet Alexandra Moraru
Maria Moitinho de Almeida
Jean-Marie Degryse
author_sort Alexandra Moraru
title PALTEM: What Parameters Should Be Collected in Disaster Settings to Assess the Long-Term Outcomes of Famine?
title_short PALTEM: What Parameters Should Be Collected in Disaster Settings to Assess the Long-Term Outcomes of Famine?
title_full PALTEM: What Parameters Should Be Collected in Disaster Settings to Assess the Long-Term Outcomes of Famine?
title_fullStr PALTEM: What Parameters Should Be Collected in Disaster Settings to Assess the Long-Term Outcomes of Famine?
title_full_unstemmed PALTEM: What Parameters Should Be Collected in Disaster Settings to Assess the Long-Term Outcomes of Famine?
title_sort paltem: what parameters should be collected in disaster settings to assess the long-term outcomes of famine?
publisher MDPI AG
series International Journal of Environmental Research and Public Health
issn 1660-4601
publishDate 2018-04-01
description Evidence suggests that nutritional status during fetal development and early life leaves an imprint on the genome, which leads to health outcomes not only on a person as an adult but also on his offspring. The purpose of this study is to bring forth an overview of the relevant parameters that need to be collected to assess the long-term and transgenerational health outcomes of famine. A literature search was conducted for the most pertinent articles on the epigenetic effects of famine. The results were compiled, synthesized and discussed with an expert in genetics for critical input and validation. Prenatal and early life exposure to famine was associated with metabolic, cardiovascular, respiratory, reproductive, neuropsychiatric and oncologic diseases. We propose a set of parameters to be collected in disaster settings to assess the long-term outcomes of famine: PALTEM (parameters to assess long-term effects of malnutrition).
topic environmental epigenetics
DNA methylation
life-stage exposure
famine
risk assessment
url http://www.mdpi.com/1660-4601/15/5/857
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AT jeanmariedegryse paltemwhatparametersshouldbecollectedindisastersettingstoassessthelongtermoutcomesoffamine
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