Wnt-5a Promotes Neural Development and Differentiation by Regulating CDK5 via Ca2+/Calpain Pathway
Background/Aims: The Wnt signaling pathway has essential functions in the central nervous system, where it regulates the major physiological functions of neurons, including development, differentiation, and plasticity. Wnt signaling controls these cellular events; however, how Wnt pathways integrate...
Main Authors: | Yang Shu, Min Xiang, Pei Zhang, Guangjian Qi, Feng He, Qian Zhang, Zheng Zhang, Zexi Lv, Xiang Peng, Hongwei Cai, Bo Tian |
---|---|
Format: | Article |
Language: | English |
Published: |
Cell Physiol Biochem Press GmbH & Co KG
2018-12-01
|
Series: | Cellular Physiology and Biochemistry |
Subjects: | |
Online Access: | https://www.karger.com/Article/FullText/495932 |
Similar Items
-
Dopamine signaling negatively regulates striatal phosphorylation of Cdk5 at tyrosine 15 in mice.
by: Yukio eYamamura, et al.
Published: (2013-02-01) -
Roscovitine, a Cyclin-Dependent Kinase-5 Inhibitor, Decreases Phosphorylated Tau Formation and Death of Retinal Ganglion Cells of Rats after Optic Nerve Crush
by: Takahisa Hirokawa, et al.
Published: (2021-07-01) -
Canonical Wnt Signaling Protects Hippocampal Neurons from Aβ Oligomers: Role of Non-Canonical Wnt-5a/Ca2+ in Mitochondrial Dynamics
by: Carmen eSilva-Alvarez, et al.
Published: (2013-06-01) -
Neurogenesis and gliogenesis modulation in cerebral ischemia by CDK5 RNAi-based therapy
by: Juan Ignacio Muñoz-Manco, et al.
Published: (2018-09-01) -
Mouse Model of Congenital Heart Defects, Dysmorphic Facial Features and Intellectual Developmental Disorders as a Result of Non-functional CDK13
by: Monika Nováková, et al.
Published: (2019-08-01)