Class II transactivator (CIITA) enhances cytoplasmic processing of HIV-1 Pr55Gag.

Class II transactivator (CIITA) enhances cytoplasmic processing of HIV-1 Pr55Gag.

The Pr55(gag) (Gag) polyprotein of HIV serves as a scaffold for virion assembly and is thus essential for progeny virion budding and maturation. Gag localizes to the plasma membrane (PM) and membranes of late endosomes, allowing for release of infectious virus directly from the cell membrane and/or...

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Bibliographic Details
Main Authors:	Kristen A Porter, Lauren N Kelley, Annette George, Jonathan A Harton, Karen M Duus
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-06-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC2892040?pdf=render

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