Mini Review: Correlations of Cognitive Domains With Cerebrospinal Fluid α-Synuclein Levels in Patients With Parkinson's Disease

Mini Review: Correlations of Cognitive Domains With Cerebrospinal Fluid α-Synuclein Levels in Patients With Parkinson's Disease

The level of α-synuclein, a component of Lewy bodies, in cerebrospinal fluid (CSF) in Parkinson's disease (PD) has attracted recent attention. Most meta-analyses conclude that CSF levels of α-synuclein are decreased in PD. Patients with PD present with cognitive impairment, including frontal/ex...

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Bibliographic Details
Main Authors: Hidetomo Murakami, Kenjiro Ono, Tomotaka Shiraishi, Tadashi Umehara, Shusaku Omoto, Yasuyuki Iguchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Aging Neuroscience
Subjects:
Parkinson's disease
cerebrospinal fluid
α-synuclein
Lewy body
cognitive domain
frontal/executive function
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2020.616357/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2020.616357/full

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