Clinicopathological and prognostic correlations of HER3 expression and its degradation regulators, NEDD4–1 and NRDP1, in primary breast cancer

Clinicopathological and prognostic correlations of HER3 expression and its degradation regulators, NEDD4–1 and NRDP1, in primary breast cancer

Abstract Background Human epidermal growth factor receptor HER3 (ErbB3), especially in association with its relative HER2 (ErbB2), is known as a key oncogene in breast tumour biology. Nonetheless, the prognostic relevance of HER3 remains controversial. NEDD4–1 and NRDP1 are signalling molecules clos...

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Bibliographic Details
Main Authors: Satu Luhtala, Synnöve Staff, Anne Kallioniemi, Minna Tanner, Jorma Isola
Format: Article
Language:English
Published: BMC 2018-10-01
Series:BMC Cancer
Subjects:
HER3
ErbB3
NEDD4–1
NRDP1
FLRF
RNF41
Online Access:http://link.springer.com/article/10.1186/s12885-018-4917-1

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http://link.springer.com/article/10.1186/s12885-018-4917-1

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