Gene expression analysis of PTEN positive glioblastoma stem cells identifies DUB3 and Wee1 modulation in a cell differentiation model.

Gene expression analysis of PTEN positive glioblastoma stem cells identifies DUB3 and Wee1 modulation in a cell differentiation model.

The term astrocytoma defines a quite heterogeneous group of neoplastic diseases that collectively represent the most frequent brain tumors in humans. Among them, glioblastoma multiforme represents the most malignant form and its associated prognosis is one of the poorest among tumors of the central...

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Main Authors: Stefano Forte, Alfredo Pagliuca, Eugenia T Maniscalchi, Rosario Gulino, Giovanna Calabrese, Lucia Ricci-Vitiani, Roberto Pallini, Michele Signore, Rosalba Parenti, Ruggero De Maria, Massimo Gulisano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3861258?pdf=render

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