Nerve Growth Factor Induces Proliferation and Aggressiveness in Prostate Cancer Cells

Nerve Growth Factor Induces Proliferation and Aggressiveness in Prostate Cancer Cells

Resistance to hormone therapy and disease progression is the major challenge in clinical management of prostate cancer (PC). Drugs currently used in PC therapy initially show a potent antitumor effects, but PC gradually develops resistance, relapses and spreads. Most patients who fail primary therap...

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Bibliographic Details
Main Authors: Marzia Di Donato, Gustavo Cernera, Antimo Migliaccio, Gabriella Castoria
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cancers
Subjects:
NGF/TrkA signaling
mitogenesis
invasiveness
EMT
3D models
castrate-resistant prostate cancers
Online Access:https://www.mdpi.com/2072-6694/11/6/784

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