Limitations when use chloramphenicol-bcyclodextrins complexes in ophtalmic solutions buffered with boric acid/borax system

Chloramphenicol eye drops are commonly prescribed in concentrations of 0.5-1% in the treatment of infectious conjunctivitis. In terms of ophthalmic solution preparation, the major disadvantage of chloramphenicol consists in its low solubility in water. The solubility is increased by substances that...

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Bibliographic Details
Main Authors: Todoran Nicoleta, Ciurba Adriana, Rédai Emőke, Ion V., Lazăr Luminița, Sipos Emese
Format: Article
Language:English
Published: Sciendo 2014-12-01
Series:Acta Medica Marisiensis
Subjects:
Online Access:https://doi.org/10.1515/amma-2015-0007