Interleukin-6 Interweaves the Bone Marrow Microenvironment, Bone Loss, and Multiple Myeloma

Interleukin-6 Interweaves the Bone Marrow Microenvironment, Bone Loss, and Multiple Myeloma

The immune system is strongly linked to the maintenance of healthy bone. Inflammatory cytokines, specifically, are crucial to skeletal homeostasis and any dysregulation can result in detrimental health complications. Interleukins, such as interleukin 6 (IL-6), act as osteoclast differentiation modul...

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Bibliographic Details
Main Authors: Danielle Harmer, Carolyne Falank, Michaela R. Reagan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Endocrinology
Subjects:
multiple myeloma
IL-6
interleukin 6
bone marrow
MSCs
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00788/full

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