Bovine FcRn-mediated human immunoglobulin G transfer across the milk-blood barrier in transgenic mice.

Maternal-fetal IgGs transport occurs either prenatally or postnatally, which confers the newborns with passive immunity before their own immune system has matured. However, little is known about the mechanisms of postnatal IgGs passage in the mammary gland. To investigate how FcRn mediates the IgGs...

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Bibliographic Details
Main Authors: Dan Cui, Linlin Zhang, Jia Li, Yaofeng Zhao, Xiaoxiang Hu, Yunping Dai, Ran Zhang, Ning Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4278800?pdf=render