Conjugation of Human β-Defensin 2 to Spike Protein Receptor-Binding Domain Induces Antigen-Specific Protective Immunity against Middle East Respiratory Syndrome Coronavirus Infection in Human Dipeptidyl Peptidase 4 Transgenic Mice

Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe acute respiratory symptoms. Due to the lack of medical countermeasures, effective and safe vaccines against MERS-CoV infection are urgently required. Although different types of candidate vaccines have been developed, their immuno...

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Bibliographic Details
Main Authors: Ju Kim, Ye Lin Yang, Yongsu Jeong, Yong-Suk Jang
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Vaccines
Subjects:
Online Access:https://www.mdpi.com/2076-393X/8/4/635