Phosphorylation of Phylogenetically Conserved Amino Acid Residues Confines HBx within Different Cell Compartments of Human Hepatocarcinoma Cells
Hepatitis B virus (HBV) is a circular, and partially double-stranded DNA virus. Upon infection, the viral genome is translocated into the cell nucleus, generating the covalently closed circular DNA (cccDNA) intermediate, and forming a mini chromosome. HBV HBx is a small protein displaying multiple r...
Main Authors: | Cristian Prieto, Juan Montecinos, Gustavo Jiménez, Constanza Riquelme, Daniel Garrido, Sergio Hernández, Alejandra Loyola, Rodrigo A. Villanueva |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
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Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/5/1254 |
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