Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly.

Structural and functional studies of nonstructural protein 2 of the hepatitis C virus reveal its key role as organizer of virion assembly.

Non-structural protein 2 (NS2) plays an important role in hepatitis C virus (HCV) assembly, but neither the exact contribution of this protein to the assembly process nor its complete structure are known. In this study we used a combination of genetic, biochemical and structural methods to decipher...

Full description

Bibliographic Details
Main Authors: Vlastimil Jirasko, Roland Montserret, Ji Young Lee, Jérôme Gouttenoire, Darius Moradpour, Francois Penin, Ralf Bartenschlager
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21187906/pdf/?tool=EBI

Similar Items

Similar Items