Methylation of cell-free circulating DNA in the diagnosis of cancer

A range of molecular alterations found in tumor cells, such as DNA mutations and methylation changes, is also reflected in cell-free circulating DNA (circDNA) released from the tumor into the blood, thereby making circDNA an ideal candidate for the basis of a blood-based cancer diagnosis test. In ma...

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Bibliographic Details
Main Authors: Goli eSamimi, Kristina eWarton
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmolb.2015.00013/full