Network-based analysis of oligodendrogliomas predicts novel cancer gene candidates within the region of the 1p/19q co-deletion

Network-based analysis of oligodendrogliomas predicts novel cancer gene candidates within the region of the 1p/19q co-deletion

Abstract Oligodendrogliomas are primary human brain tumors with a characteristic 1p/19q co-deletion of important prognostic relevance, but little is known about the pathology of this chromosomal mutation. We developed a network-based approach to identify novel cancer gene candidates in the region of...

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Bibliographic Details
Main Authors: Josef Gladitz, Barbara Klink, Michael Seifert
Format: Article
Language:English
Published: BMC 2018-06-01
Series:Acta Neuropathologica Communications
Subjects:
Oligodendrogliomas
1p/19q co-deletion
Network biology
Network inference
Network propagation
Cancer genomics
Online Access:http://link.springer.com/article/10.1186/s40478-018-0544-y

Internet

http://link.springer.com/article/10.1186/s40478-018-0544-y

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