Use of Information Measures and Their Approximations to Detect Predictive Gene-Gene Interaction

Use of Information Measures and Their Approximations to Detect Predictive Gene-Gene Interaction

We reconsider the properties and relationships of the interaction information and its modified versions in the context of detecting the interaction of two SNPs for the prediction of a binary outcome when interaction information is positive. This property is called predictive interaction, and we stat...

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Bibliographic Details
Main Authors: Jan Mielniczuk, Marcin Rdzanowski
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Entropy
Subjects:
predictive interaction
interaction information
logistic interaction
Single Nucleotide Polymorphism (SNP)
copula
Kirkwood approximation and parameter
Online Access:http://www.mdpi.com/1099-4300/19/1/23

Internet

http://www.mdpi.com/1099-4300/19/1/23

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