Ionizing Radiation Does Not Alter the Antitumor Activity of Herpes Simplex Virus Vector G207 in Subcutaneous Tumor Models of Human and Murine Prostate Cancer

Ionizing Radiation Does Not Alter the Antitumor Activity of Herpes Simplex Virus Vector G207 in Subcutaneous Tumor Models of Human and Murine Prostate Cancer

Viral gene therapy against malignant tumors holds great promise for tumors that are susceptible to the oncolytic activity of viruses. One advantage of oncolytic viral therapy is that it can potentially be combined with other therapies, such as radiotherapy, to obtain an enhanced tumor response. In...

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Bibliographic Details
Main Authors: Timothy J. Jorgensen, Sanford Katz, Ellen K. Wittmack, Susan Varghese, Tomoki Todo, Samuel D. Rabkin, Robert L. Martuza
Format: Article
Language:English
Published: Elsevier 2001-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
herpes virus
gene therapy
prostate cancer
radiotherapy
oncolytic virus
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558601800592

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