Epigenetic regulation of human SOX3 gene expression during early phases of neural differentiation of NT2/D1 cells.

Epigenetic regulation of human SOX3 gene expression during early phases of neural differentiation of NT2/D1 cells.

Sox3/SOX3 is one of the earliest neural markers in vertebrates. Together with the Sox1/SOX1 and Sox2/SOX2 genes it is implicated in the regulation of stem cell identity. In the present study, we performed the first analysis of epigenetic mechanisms (DNA methylation and histone marks) involved in the...

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Bibliographic Details
Main Authors: Vladanka Topalovic, Aleksandar Krstic, Marija Schwirtlich, Diletta Dolfini, Roberto Mantovani, Milena Stevanovic, Marija Mojsin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5590877?pdf=render

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