EARLY TARGETED TREATMENT OF SEPTIC SHOCK: RESULTS OF MULTICENTER RETROSPECTIVE STUDY

EARLY TARGETED TREATMENT OF SEPTIC SHOCK: RESULTS OF MULTICENTER RETROSPECTIVE STUDY

Multicenter, retrospective, cohort study was conducted enrolling 727 patients suffering from septic shock as a complication of extensive peritonitis (abdominal sepsis). Patients were treated in eight intensive care departments of eight medical units. Outcomes were compared depending on the applied t...

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Bibliographic Details
Main Authors: L. L. Plotkin, I. Yu. Smolensky, N. N. Timchenko, I. P. Shapko, N. N. Safronova, A. G. Konashev, I. S. Edelshtein
Format: Article
Language:Russian
Published: NEW TERRA Publishing House 2017-11-01
Series:Вестник анестезиологии и реаниматологии
Subjects:
septic shock
early targeted therapy
Online Access:https://www.vair-journal.com/jour/article/view/14
Description
Summary:Multicenter, retrospective, cohort study was conducted enrolling 727 patients suffering from septic shock as a complication of extensive peritonitis (abdominal sepsis). Patients were treated in eight intensive care departments of eight medical units. Outcomes were compared depending on the applied tactics (using algorithm of early targeted therapy of septic shock in accordance with international recommendations and local approaches typical for a certain unit). It has been found out that the algorithm of early targeted therapy was used unreasonably rearly (in 27% of patients in the study subpopulation). However its application allowed reducing the mortality by 12% and increasing 28-day survival period.
ISSN:2078-5658
2541-8653

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