Procyanidins from Wild Grape (Vitis amurensis) Seeds Regulate ARE-Mediated Enzyme Expression via Nrf2 Coupled with p38 and PI3K/Akt Pathway in HepG2 Cells

Procyanidins from Wild Grape (Vitis amurensis) Seeds Regulate ARE-Mediated Enzyme Expression via Nrf2 Coupled with p38 and PI3K/Akt Pathway in HepG2 Cells

Procyanidins, polymers of flavan-3-ol units, have been reported to exhibit many beneficial health effects such as antioxidant and anti-carcinogenic effects. In this study, we investigated the cancer chemopreventive properties of procyanidins from wild grape (Vitis amurensis) seeds in particular thei...

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Bibliographic Details
Main Authors: Woo-Sik Jeong, Mira Jun, Min-Ji Bak
Format: Article
Language:English
Published: MDPI AG 2012-01-01
Series:International Journal of Molecular Sciences
Subjects:
wild grape seed
Vitis amurensis
procyanidin
chemoprevention
MAPKs
Nrf2
phase II detoxifying enzyme
antioxidant enzyme
Online Access:http://www.mdpi.com/1422-0067/13/1/801/

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http://www.mdpi.com/1422-0067/13/1/801/

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