How Shigella utilizes Ca2+ jagged edge signals during invasion of epithelial cells

How Shigella utilizes Ca2+ jagged edge signals during invasion of epithelial cells

Shigella, the causative agent of bacillary dysentery invades intestinal epithelial cells using a type III secretion system (T3SS). Through the injection of type III effectors, Shigella manipulates the actin cytoskeleton to induce its internalization in epithelial cells. At early invasion stages, Shi...

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Bibliographic Details
Main Authors: Mariette eBonnet, Guy eTran Van Nhieu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Inflammation
Ca2+ signaling
Shigella invasion
mitochondria-induced cell death
host cell survival
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2016.00016/full

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