Acute and Chronic Dopaminergic Depletion Differently Affect Motor Thalamic Function
The motor thalamus (MTh) plays a crucial role in the basal ganglia (BG)-cortical loop in motor information codification. Despite this, there is limited evidence of MTh functionality in normal and Parkinsonian conditions. To shed light on the functional properties of the MTh, we examined the effects...
Main Authors: | Giuseppe Di Giovanni, Laura Clara Grandi, Ernesto Fedele, Gergely Orban, Agnese Salvadè, Wei Song, Eleonora Cuboni, Alessandro Stefani, Alain Kaelin-Lang, Salvatore Galati |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-04-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/8/2734 |
Similar Items
-
Microdialysis as a Tool in Studies of L-Dopa and Metabolites in Malignant Melanoma and Parkinson’s Disease
by: Dizdar (Segrell), Nil
Published: (1999) -
Intrastriatal inhibition of aromatic amino acid decarboxylase prevents l-DOPA-induced dyskinesia: A bilateral reverse in vivo microdialysis study in 6-hydroxydopamine lesioned rats
by: Kerstin Buck, et al.
Published: (2008-02-01) -
Oscillatory Activity in the Cortex, Motor Thalamus and Nucleus Reticularis Thalami in Acute TTX and Chronic 6-OHDA Dopamine-Depleted Animals
by: Laura C. Grandi, et al.
Published: (2018-08-01) -
Impairment of Serotonergic Transmission by the Antiparkinsonian Drug L-DOPA: Mechanisms and Clinical Implications
by: Cristina Miguelez, et al.
Published: (2017-09-01) -
Chronic L-DOPA therapy alters central serotonergic function and L-DOPA-induced dopamine release in a region-dependent manner in a rat model of Parkinson's disease
by: Sylvia Navailles, et al.
Published: (2011-02-01)