Genetic variation in the β2-adrenocepter gene is associated with susceptibility to bacterial meningitis in adults.

Genetic variation in the β2-adrenocepter gene is associated with susceptibility to bacterial meningitis in adults.

Recently, the biased β2-adrenoceptor/β-arrestin pathway was shown to play a pivotal role in crossing of the blood brain barrier by Neisseria meningitidis. We hypothesized that genetic variation in the β2-adrenoceptor gene (ADRB2) may influence susceptibility to bacterial meningitis. In a prospective...

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Bibliographic Details
Main Authors: Kirsten S Adriani, Matthijs C Brouwer, Frank Baas, Aeilko H Zwinderman, Arie van der Ende, Diederik van de Beek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22624056/pdf/?tool=EBI

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