Radiosynthesis, In Vivo Biological Evaluation, and Imaging of Brain Lesions with [123I]-CLINME, a New SPECT Tracer for the Translocator Protein

Radiosynthesis, In Vivo Biological Evaluation, and Imaging of Brain Lesions with [123I]-CLINME, a New SPECT Tracer for the Translocator Protein

The high affinity translocator protein (TSPO) ligand 6-chloro-2-(4′-iodophenyl)-3-(N,N-methylethyl)imidazo[1,2-a]pyridine-3-acetamide (CLINME) was radiolabelled with iodine-123 and assessed for its sensitivity for the TSPO in rodents. Moreover neuroinflammatory changes on a unilateral excitotoxic le...

Full description

Bibliographic Details
Main Authors: F. Mattner, M. Quinlivan, I. Greguric, T. Pham, X. Liu, T. Jackson, P. Berghofer, C. J. R. Fookes, B. Dikic, M.-C. Gregoire, F. Dolle, A. Katsifis
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:Disease Markers
Online Access:http://dx.doi.org/10.1155/2015/729698

Similar Items

Similar Items