Exo-Functionalized Metallacages as Host-Guest Systems for the Anticancer Drug Cisplatin

Within the framework of designing new self-assembled metallosupramolecular architectures for drug delivery, seven [Pd2L4]4+ metallacages (L = 2,6-bis(pyridine-3-ylethynyl)pyridine) featuring different groups in exo-position, selected to enhance the cage solubility in aqueous environment, were synthe...

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Bibliographic Details
Main Authors: Ben Woods, Margot N. Wenzel, Thomas Williams, Sophie R. Thomas, Robert L. Jenkins, Angela Casini
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2019.00068/full