Central liponeurocytoma: Case report and review of literature

• Main Authors: Pankaj Ailawadhi, P. Sarat Chandra, M.C. Sharma, A.K. Mahapatra
• Format: Article
• Language: English
• Published: Thieme Medical Publishers, Inc. 2012-01-01
• Series: Indian Journal of Neurosurgery
• Subjects: central liponeurocytoma; cerebellar liponeurocytoma; glioneural tumors
• Online Access: http://www.thieme-connect.de/DOI/DOI?10.4103/2277-9167.94379

Cerebellar liponeurocytoma consists of well-differentiated neurons with the cytology of neurocytes in addition to a population of lipidized cells. Hence it is biphasic in appearance and has been included in the category of glioneuronal tumors of the central nervous system by the WHO working group on the Classification of Tumors of the Nervous System. However, liponeurocytoma is not exclusive to the cerebellar or fourth ventricular location. Since its inclusion in the central nervous system tumor classification, nine cases with similar histological and immunohistochemical features have also been described in the lateral ventricles. We describe here such a lateral ventricular tumour in a 30-year-old woman, characteristically showing divergent glio-neuronal differentiation and lipidized neoplastic cells. Therefore, we suggest that future WHO tumor classification should consider that liponeurocytomas are not entirely restricted to the cerebellum and henceforth change of nomenclature might be considered, as also pointed out by other authors.