Quantitative trait loci for interhemispheric commissure development and social behaviors in the BTBR T⁺ tf/J mouse model of autism.

Quantitative trait loci for interhemispheric commissure development and social behaviors in the BTBR T⁺ tf/J mouse model of autism.

Autism and Agenesis of the Corpus Callosum (AgCC) are interrelated behavioral and anatomic phenotypes whose genetic etiologies are incompletely understood. We used the BTBR T⁺ tf/J (BTBR) strain, exhibiting fully penetrant AgCC, a diminished hippocampal commissure, and abnormal behaviors that may ha...

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Bibliographic Details
Main Authors: Dorothy M Jones-Davis, Mu Yang, Eric Rider, Nathan C Osbun, Gilberto J da Gente, Jiang Li, Adam M Katz, Michael D Weber, Saunak Sen, Jacqueline Crawley, Elliott H Sherr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3626795?pdf=render

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