Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de Parkinson
The aim of this study is to analyze executive function and motor symptoms in patients with idiopathic Parkinson's disease (PD). The sample consisted of 44 subjects with PD between the ages of 45 to 75, who were examined consecutively. The subjects were divided into two groups according to the d...
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doaj-2f67a1e854524c51a5bc1824232b3f172020-11-24T22:32:05ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria0004-282X1678-42272010-04-0168224625110.1590/S0004-282X2010000200018Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de ParkinsonIndira Silveira Campos-SousaRaimundo Nonato Campos-SousaLuiz Ataíde JrMarta Maria de Brito SoaresKelson James AlmeidaThe aim of this study is to analyze executive function and motor symptoms in patients with idiopathic Parkinson's disease (PD). The sample consisted of 44 subjects with PD between the ages of 45 to 75, who were examined consecutively. The subjects were divided into two groups according to the duration of the disease. The control group was composed of spouses, family and accompanying members. Patients included were submitted to motor dysfunction evaluation using the UPDRS. The executive functions modalities analyzed included: operational memory, inhibitory control, planning, cognitive flexibility and inductive reasoning. Significant differences between the experimental and control groups were found in all the executive domains studied. Evidence of tremor, rigidity and bradykinesia correlation with executive dysfunction were not observed. Patients with PD, even in the initial phase of the disease, presented executive dysfunction. The cardinal motor signs of the disease were not correlated with the cognitive dysfunction found.<br>O objetivo do estudo é avaliar as funções executivas e sintomas motores em pacientes portadores de doença de Parkinson. A amostra se constituiu de 44 portadores de doença de Parkinson com idade entre 45 e 75 anos, examinados consecutivamente, os quais foram divididos em dois grupos de acordo com o tempo de duração da doença. O grupo controle foi composto de acompanhantes ou cônjuges. Os sujeitos selecionados foram submetidos à avaliação motora utilizando-se a escala UPDRS e à avaliação das funções executivas nas modalidades: raciocínio indutivo, memória operacional, controle inibitório, planejamento e flexibilidade cognitiva. Os resultados apontaram diferenças significantes entre os grupos experimentais e controle nas modalidades analisadas. Não encontramos evidência de associação entre tremor, rigidez e bradicinesia com as funções executivas. Conclui-se que os pacientes com doença de Parkinson, mesmo nas fases iniciais da doença, apresentam comprometimento cognitivo executivo. Os sintomas motores da doença não estavam correlacionados às disfunções executivas.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000200018neuropsicologiatestes neuropsicológicosfunções executivasdoença de Parkinsonneuropsychologyneuropsychological testsexecutive functionsidiopathic Parkinson's disease |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Indira Silveira Campos-Sousa Raimundo Nonato Campos-Sousa Luiz Ataíde Jr Marta Maria de Brito Soares Kelson James Almeida |
spellingShingle |
Indira Silveira Campos-Sousa Raimundo Nonato Campos-Sousa Luiz Ataíde Jr Marta Maria de Brito Soares Kelson James Almeida Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de Parkinson Arquivos de Neuro-Psiquiatria neuropsicologia testes neuropsicológicos funções executivas doença de Parkinson neuropsychology neuropsychological tests executive functions idiopathic Parkinson's disease |
author_facet |
Indira Silveira Campos-Sousa Raimundo Nonato Campos-Sousa Luiz Ataíde Jr Marta Maria de Brito Soares Kelson James Almeida |
author_sort |
Indira Silveira Campos-Sousa |
title |
Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de Parkinson |
title_short |
Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de Parkinson |
title_full |
Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de Parkinson |
title_fullStr |
Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de Parkinson |
title_full_unstemmed |
Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de Parkinson |
title_sort |
executive dysfunction and motor symptoms in parkinson's disease disfunções executivas e sintomas motores na doença de parkinson |
publisher |
Academia Brasileira de Neurologia (ABNEURO) |
series |
Arquivos de Neuro-Psiquiatria |
issn |
0004-282X 1678-4227 |
publishDate |
2010-04-01 |
description |
The aim of this study is to analyze executive function and motor symptoms in patients with idiopathic Parkinson's disease (PD). The sample consisted of 44 subjects with PD between the ages of 45 to 75, who were examined consecutively. The subjects were divided into two groups according to the duration of the disease. The control group was composed of spouses, family and accompanying members. Patients included were submitted to motor dysfunction evaluation using the UPDRS. The executive functions modalities analyzed included: operational memory, inhibitory control, planning, cognitive flexibility and inductive reasoning. Significant differences between the experimental and control groups were found in all the executive domains studied. Evidence of tremor, rigidity and bradykinesia correlation with executive dysfunction were not observed. Patients with PD, even in the initial phase of the disease, presented executive dysfunction. The cardinal motor signs of the disease were not correlated with the cognitive dysfunction found.<br>O objetivo do estudo é avaliar as funções executivas e sintomas motores em pacientes portadores de doença de Parkinson. A amostra se constituiu de 44 portadores de doença de Parkinson com idade entre 45 e 75 anos, examinados consecutivamente, os quais foram divididos em dois grupos de acordo com o tempo de duração da doença. O grupo controle foi composto de acompanhantes ou cônjuges. Os sujeitos selecionados foram submetidos à avaliação motora utilizando-se a escala UPDRS e à avaliação das funções executivas nas modalidades: raciocínio indutivo, memória operacional, controle inibitório, planejamento e flexibilidade cognitiva. Os resultados apontaram diferenças significantes entre os grupos experimentais e controle nas modalidades analisadas. Não encontramos evidência de associação entre tremor, rigidez e bradicinesia com as funções executivas. Conclui-se que os pacientes com doença de Parkinson, mesmo nas fases iniciais da doença, apresentam comprometimento cognitivo executivo. Os sintomas motores da doença não estavam correlacionados às disfunções executivas. |
topic |
neuropsicologia testes neuropsicológicos funções executivas doença de Parkinson neuropsychology neuropsychological tests executive functions idiopathic Parkinson's disease |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000200018 |
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