Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de Parkinson

The aim of this study is to analyze executive function and motor symptoms in patients with idiopathic Parkinson's disease (PD). The sample consisted of 44 subjects with PD between the ages of 45 to 75, who were examined consecutively. The subjects were divided into two groups according to the d...

Full description

Bibliographic Details
Main Authors: Indira Silveira Campos-Sousa, Raimundo Nonato Campos-Sousa, Luiz Ataíde Jr, Marta Maria de Brito Soares, Kelson James Almeida
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2010-04-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000200018
id doaj-2f67a1e854524c51a5bc1824232b3f17
record_format Article
spelling doaj-2f67a1e854524c51a5bc1824232b3f172020-11-24T22:32:05ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria0004-282X1678-42272010-04-0168224625110.1590/S0004-282X2010000200018Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de ParkinsonIndira Silveira Campos-SousaRaimundo Nonato Campos-SousaLuiz Ataíde JrMarta Maria de Brito SoaresKelson James AlmeidaThe aim of this study is to analyze executive function and motor symptoms in patients with idiopathic Parkinson's disease (PD). The sample consisted of 44 subjects with PD between the ages of 45 to 75, who were examined consecutively. The subjects were divided into two groups according to the duration of the disease. The control group was composed of spouses, family and accompanying members. Patients included were submitted to motor dysfunction evaluation using the UPDRS. The executive functions modalities analyzed included: operational memory, inhibitory control, planning, cognitive flexibility and inductive reasoning. Significant differences between the experimental and control groups were found in all the executive domains studied. Evidence of tremor, rigidity and bradykinesia correlation with executive dysfunction were not observed. Patients with PD, even in the initial phase of the disease, presented executive dysfunction. The cardinal motor signs of the disease were not correlated with the cognitive dysfunction found.<br>O objetivo do estudo é avaliar as funções executivas e sintomas motores em pacientes portadores de doença de Parkinson. A amostra se constituiu de 44 portadores de doença de Parkinson com idade entre 45 e 75 anos, examinados consecutivamente, os quais foram divididos em dois grupos de acordo com o tempo de duração da doença. O grupo controle foi composto de acompanhantes ou cônjuges. Os sujeitos selecionados foram submetidos à avaliação motora utilizando-se a escala UPDRS e à avaliação das funções executivas nas modalidades: raciocínio indutivo, memória operacional, controle inibitório, planejamento e flexibilidade cognitiva. Os resultados apontaram diferenças significantes entre os grupos experimentais e controle nas modalidades analisadas. Não encontramos evidência de associação entre tremor, rigidez e bradicinesia com as funções executivas. Conclui-se que os pacientes com doença de Parkinson, mesmo nas fases iniciais da doença, apresentam comprometimento cognitivo executivo. Os sintomas motores da doença não estavam correlacionados às disfunções executivas.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000200018neuropsicologiatestes neuropsicológicosfunções executivasdoença de Parkinsonneuropsychologyneuropsychological testsexecutive functionsidiopathic Parkinson's disease
collection DOAJ
language English
format Article
sources DOAJ
author Indira Silveira Campos-Sousa
Raimundo Nonato Campos-Sousa
Luiz Ataíde Jr
Marta Maria de Brito Soares
Kelson James Almeida
spellingShingle Indira Silveira Campos-Sousa
Raimundo Nonato Campos-Sousa
Luiz Ataíde Jr
Marta Maria de Brito Soares
Kelson James Almeida
Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de Parkinson
Arquivos de Neuro-Psiquiatria
neuropsicologia
testes neuropsicológicos
funções executivas
doença de Parkinson
neuropsychology
neuropsychological tests
executive functions
idiopathic Parkinson's disease
author_facet Indira Silveira Campos-Sousa
Raimundo Nonato Campos-Sousa
Luiz Ataíde Jr
Marta Maria de Brito Soares
Kelson James Almeida
author_sort Indira Silveira Campos-Sousa
title Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de Parkinson
title_short Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de Parkinson
title_full Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de Parkinson
title_fullStr Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de Parkinson
title_full_unstemmed Executive dysfunction and motor symptoms in Parkinson's disease Disfunções executivas e sintomas motores na doença de Parkinson
title_sort executive dysfunction and motor symptoms in parkinson's disease disfunções executivas e sintomas motores na doença de parkinson
publisher Academia Brasileira de Neurologia (ABNEURO)
series Arquivos de Neuro-Psiquiatria
issn 0004-282X
1678-4227
publishDate 2010-04-01
description The aim of this study is to analyze executive function and motor symptoms in patients with idiopathic Parkinson's disease (PD). The sample consisted of 44 subjects with PD between the ages of 45 to 75, who were examined consecutively. The subjects were divided into two groups according to the duration of the disease. The control group was composed of spouses, family and accompanying members. Patients included were submitted to motor dysfunction evaluation using the UPDRS. The executive functions modalities analyzed included: operational memory, inhibitory control, planning, cognitive flexibility and inductive reasoning. Significant differences between the experimental and control groups were found in all the executive domains studied. Evidence of tremor, rigidity and bradykinesia correlation with executive dysfunction were not observed. Patients with PD, even in the initial phase of the disease, presented executive dysfunction. The cardinal motor signs of the disease were not correlated with the cognitive dysfunction found.<br>O objetivo do estudo é avaliar as funções executivas e sintomas motores em pacientes portadores de doença de Parkinson. A amostra se constituiu de 44 portadores de doença de Parkinson com idade entre 45 e 75 anos, examinados consecutivamente, os quais foram divididos em dois grupos de acordo com o tempo de duração da doença. O grupo controle foi composto de acompanhantes ou cônjuges. Os sujeitos selecionados foram submetidos à avaliação motora utilizando-se a escala UPDRS e à avaliação das funções executivas nas modalidades: raciocínio indutivo, memória operacional, controle inibitório, planejamento e flexibilidade cognitiva. Os resultados apontaram diferenças significantes entre os grupos experimentais e controle nas modalidades analisadas. Não encontramos evidência de associação entre tremor, rigidez e bradicinesia com as funções executivas. Conclui-se que os pacientes com doença de Parkinson, mesmo nas fases iniciais da doença, apresentam comprometimento cognitivo executivo. Os sintomas motores da doença não estavam correlacionados às disfunções executivas.
topic neuropsicologia
testes neuropsicológicos
funções executivas
doença de Parkinson
neuropsychology
neuropsychological tests
executive functions
idiopathic Parkinson's disease
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2010000200018
work_keys_str_mv AT indirasilveiracampossousa executivedysfunctionandmotorsymptomsinparkinsonsdiseasedisfuncoesexecutivasesintomasmotoresnadoencadeparkinson
AT raimundononatocampossousa executivedysfunctionandmotorsymptomsinparkinsonsdiseasedisfuncoesexecutivasesintomasmotoresnadoencadeparkinson
AT luizataidejr executivedysfunctionandmotorsymptomsinparkinsonsdiseasedisfuncoesexecutivasesintomasmotoresnadoencadeparkinson
AT martamariadebritosoares executivedysfunctionandmotorsymptomsinparkinsonsdiseasedisfuncoesexecutivasesintomasmotoresnadoencadeparkinson
AT kelsonjamesalmeida executivedysfunctionandmotorsymptomsinparkinsonsdiseasedisfuncoesexecutivasesintomasmotoresnadoencadeparkinson
_version_ 1725735166219911168