Invasive Glioblastoma Cells Acquire Stemness and Increased Akt Activation

Glioblastoma multiforme (GBM) is the most frequent and most aggressive brain tumor in adults. The dismal prognosis is due to postsurgery recurrences arising from escaped invasive tumor cells. The signaling pathways activated in invasive cells are under investigation, and models are currently design...

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Bibliographic Details
Main Authors: Jennifer R. Molina, Yuho Hayashi, Clifton Stephens, Maria-Magdalena Georgescu
Format: Article
Language:English
Published: Elsevier 2010-06-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861080003X