Unmet needs of highrisk mothers reduce success of antiretroviral treatment in HIVinfected infants

In the era of effective prevention of mother-to-child transmission of HIV, the same psychosocioeconomic factors that predispose to mother-to-child transmission also substantially increase the likelihood of antiretroviral therapy failure in infected infants. For HIV-infected infants to benefit from e...

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Bibliographic Details
Main Authors: Z Mvo, V Ntlantsana, N Bengu, J Millar, J Roider, R Bhoola, M Krishna, Y Graza, J van Lobenstein, C Kapongo, C Kogielambal, K Sprenger, M Archary, T Ndung'u, P Goulder
Format: Article
Language:English
Published: Health and Medical Publishing Group 2018-07-01
Series:South African Medical Journal
Online Access:http://www.samj.org.za/index.php/samj/article/download/12369/8574
Description
Summary:In the era of effective prevention of mother-to-child transmission of HIV, the same psychosocioeconomic factors that predispose to mother-to-child transmission also substantially increase the likelihood of antiretroviral therapy failure in infected infants. For HIV-infected infants to benefit from early infant diagnosis and treatment initiation, into which much funding and effort is now invested, it is vital that these unmet needs of high-risk mothers are urgently attended to. From an ongoing study of early infant diagnosis and treatment following in utero transmission in KwaZulu-Natal, South Africa, we describe four cases to highlight these challenges facing transmitting mothers that contribute to treatment failure in their infants.
ISSN:0256-9574
2078-5135