High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages

High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages

Macrophages are the prime innate immune cells of the inflammatory response, and the combination of multiple signaling inputs derived from the recognition of host factors [e.g., interferon-g (IFN-γ)] and invading pathogen products (e.g., toll-like receptors (TLRs) agonists) are required to maintain e...

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Bibliographic Details
Main Authors: Amitabh Das, Chul-Su Yang, Sarder Arifuzzaman, Sojin Kim, Sun Young Kim, Kyoung Hwa Jung, Young Seek Lee, Young Gyu Chai
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Immunology
Subjects:
macrophages
transcription factors
interferon-g
RNA-sequencing
lipopolysaccharide
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00022/full

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