LARP7 family proteins have conserved function in telomerase assembly
The telomerase holoenzyme is minimally composed of the reverse transcriptase and the RNA template. Here the authors identify Lar7 as a member of the full complex that helps to stabilise it and protect telomerase RNA from degradation.
Bibliographic Details
| Main Authors: |
Laura C. Collopy,
Tracy L. Ware,
Tomas Goncalves,
Sunnvør í Kongsstovu,
Qian Yang,
Hanna Amelina,
Corinne Pinder,
Ala Alenazi,
Vera Moiseeva,
Siân R. Pearson,
Christine A. Armstrong,
Kazunori Tomita |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2018-02-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-017-02296-4
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